Table 2 Comparison of predicted BGCs between genomes of the B. subtilis strains 9407 and 168
Metabolites | Type | Clusters in 9407 | Size (kb) | Clusters in 168 | Identity (%) | Bioactive spectrum |
|---|---|---|---|---|---|---|
Bacillibactin | NRPS | dhbABCEF, besA | 49.7 | dhbABCEF, besA | 99–100 | Microbial competitors |
Subtilosin A | Sactipeptide | sboA, albABCDEFG | 21.6 | sboA, albABCDEFG | 98–100 | Bacteria |
Bacilysin | NRPS | bacABCDEFG | 49.7 | bacABCDEFG | 95–100 | Bacteria, yeasts, and fungi |
Fengycin | PKS/NRPS | ppsABCDE | 82.1 | ppsABCDE | 96–98 | Filamentous fungi |
Bacillaene | PKS/NRPS | baeABCDEGHIJLMNRS, acpK | 114.8 | baeABCDEGHIJLMNRS, acpK | 98–100 | Bacteria |
Surfactin | NRPS | srfAABCD | 65.4 | srfAABCD | 98–100 | Virus, mycoplasma, and tumor |
Sublancin 168 | Glycocin | Not present | – | sunATI, bdbAB | 0 | Gram-positive bacteria |
Sporulation killing factor | Sactipeptide | Not present | – | skfABCEFGH | 0 | Bacteria |